Pyroptosisis a way of programmed cell death and the natural immune response of organisms. Creative Bioarraycanprovide customers with GSDMD/GSDME immunofluorescence staining services to better study pyroptosis.


Pyroptosisis a process of programmed inflammatory cell death. The cells continue to swell until the cell membrane ruptures, releasing a large amount of pro-inflammatory factors to stimulate other immune cells to resist infection and cause tissue inflammation. Pyroptosisusually occurs faster than apoptosis.

The mechanism of Pyroptosis The mechanism of Pyroptosis (Lieselotte Vande Walle, et al. 2016)

Our Services

When cells are subjected to different stimuli, they initiate the pyroptosis process through different pathways, and are widely involved in the occurrence and development of diseases. Our services include but are not limited to:

Pyroptosis-related Genes or Proteins Expression Level Detection

Pyrolysis can be divided into two main steps.

  • The first step (also known as the startup step):

Inflammasome recognizes extracellular bacteria, viruses, drugs and other stimuli, and promotes transcription and synthesis of pro-IL1β, Nlrp3, and caspase-11 (caspase-4, caspase-5 in human).

  • The second step (also known as the activation step):

This step is divided into the caspase-1-dependent pathway and caspase-1-independent pathway (caspase4, 5, 11 dependent pathway).

Creative Bioarray uses PCR or Western Blot to help you detect the expression level of pyrolysis-related genes or proteins, such as caspase-1\4\5\11, GSDMD, etc.

Customer Notice

Customers provide

  • Formal experimental samples
  • Target genes or proteins
  • Test purpose and requirements

We deliver

  • High-quality test reagents and antibodies
  • Experiment process
  • Complete experiment report

Experiment cycle

The time depends on the experiment content

Advantages of Our Services

  • Customized service

    Creative Bioarray can assist you to complete the design of the experimental content according to the experimental ideas, experimental literature, purpose and requirements provided by you.

  • Reliable

    The experimenters have many years of successful experiment experience in pyroptosis research and can guarantee the standard of experiment operation and experiment process.

  • Short time and low cost

    We provide customers with the most comprehensive services at the most favorable price and help customers improve the efficiency of research.

  • Safety

    All experiments have signed confidentiality agreements, focusing on protecting customer privacy.

If you are interested in our services, please contact us for more detailed information.

* For scientific research only

Online Inquiry