Amyloid Precursor Protein (APP), a transmembrane protein involved in Alzheimer's disease (AD) pathogenesis. APP can be cleaved by different enzymes, leading to the production of various fragments including amyloid-beta (Aβ) peptides, which are central to AD pathology.
Screening for inhibitors of the APP processing pathway is a crucial step in the development of potential therapeutic agents for Alzheimer's disease (AD). Creative Bioarray's modified cell lines serve as a powerful tool for studying APP processing.
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