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APP Processing Assay

Amyloid Precursor Protein (APP), a transmembrane protein involved in Alzheimer's disease (AD) pathogenesis. APP can be cleaved by different enzymes, leading to the production of various fragments including amyloid-beta (Aβ) peptides, which are central to AD pathology.

Screening for inhibitors of the APP processing pathway is a crucial step in the development of potential therapeutic agents for Alzheimer's disease (AD). Creative Bioarray's modified cell lines serve as a powerful tool for studying APP processing.

Screening for APP Processing Inhibitors

  • Cell Line for APP Processing Assay
    APP-GFP Stable Cell Line - MDCK
  • Image Analysis - Cellular Fluorescence Redistribution
  • Dose Response - Determination of IC50 Value
* For scientific research only

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