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Cell Apoptosis Assay

Introduction

Apoptosis refers to the orderly and autonomous death of cells controlled by genes in order to maintain a stable internal environment. Apoptosis is an active process of cells, involving the activation, expression and regulation of a series of genes. It is a death process that cells actively strives to better adapt to the living environment.

The main morphological feature of apoptosis is that the chromatin is fragmented into different sizes, which gather together with certain organelles, surrounded by a reflexed cell membrane, forming apoptotic bodies. Therefore, the detection methods are different according to the different stages of apoptosis. Apoptosis is a multi-step process including early, mid and late cell events, and can be detected using various cell detection methods.

Stages of apoptosis:

Early events

  • Translocation of phosphatidylserine outside the cell membrane
  • Loss of mitochondrial membrane potential
  • Release of cytochrome C and ATP
  • Activation of caspase-8 and 9

Mid-term events

  • Activation of caspase-3, 6 and 7
  • Poly-ADP-ribose polymerase (PARP) cleavage
  • Shrinkage of cells
  • Nuclease activation

Late events

  • DNA fragmentation
  • Disintegration of the nucleus
  • Formation of apoptotic bodies
  • Phagocytosis of macrophages

Our Services

With years of experience in apoptosis research, Creative Bioarray provides customers with comprehensive and professional apoptosis detection services based on highly sensitive and specific apoptosis kits and related products.

Creative Bioarray can provide a variety of methods to study apoptosis. We can establish customized research programs and provide one-stop services based on customers' requests. For a detailed introduction of each apoptosis detection service, please see below.

Our services including but not limited to:

Service Process

Creative Bioarray' technicians have superb technology and rich experience to complete various tests efficiently and accurately to ensure that the experimental data is accurate and reliable. In addition, our laboratory has advanced fluorescence microscopes and flow cytometry systems, which can provide customers with high-resolution images and enhance research results.

Notice

Notice

The customer shall be responsible for the materials and information provided, such as experimental delays or economic losses caused by invalid samples and inaccurate information provided by the customer shall be borne by the customer.

We guarantee to provide objective and unbiased experimental results, but due to the uncertainty of scientific experiments, we do not make any commitments as to whether the experimental results meet expectations.

Why Choose Us

  • Multiple choices

    We provide you with a comprehensive method to detect the apoptosis, you can choose according to your needs.

  • Professional

    We have a professional technical team, they have rich operating experience and superb technology, can ensure that the inspection is completed efficiently and accurately.

  • High quality

    We have high-quality and rich product lines, which can provide you with high-sensitivity and high-specificity apoptosis detection reagents.

  • Personalized service

    We provide a variety of apoptosis detection methods to meet customers' individual scientific research needs.

  • Low price

    We provide customers with the most comprehensive services at the most favorable price, and help customers save scientific research funds reasonably.

  • Short time

    We have a full set of testing equipment and professional experimental platform to provide customers with services in the shortest time.

If you are interested in our services, please contact us for more detailed information.

* For scientific research only

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