Drug screening for Parkinson's Disease (PD) often involves testing compounds for their potential to modulate key cellular processes associated with the disease. Calcium signaling and β-arrestin mobilization are two important cellular events that can be targeted in drug discovery efforts for PD. Calcium signaling plays a critical role in neuronal function and is disrupted in neurodegenerative diseases like PD. β-arrestins are proteins that play a role in regulating G-protein coupled receptor (GPCR) signaling, which is implicated in various cellular processes including dopaminergic signaling.
By targeting calcium signaling and β-arrestin mobilization, Creative Bioarray aims to identify compounds that can modulate key cellular processes associated with PD, potentially leading to the development of novel therapeutic interventions for the disease.