3D Spheroid Invasion Assay is a cutting-edge method for studying the invasive behavior of cells within a more physiologically relevant microenvironment compared to traditional 2D assays. This assay is particularly valuable for assessing the migratory and invasive capabilities of cells in conditions that better mimic the three-dimensional architecture of tissues. Creative Biarray offers a comprehensive solution for researchers interested in conducting 3D Spheroid Invasion Assays.
The 3D Spheroid Invasion Assay from Creative Biarray empowers researchers to explore cell invasion in a more physiologically relevant context, contributing valuable insights to fields such as cancer research, drug development, and tissue engineering. By choosing our assay, you gain access to state-of-the-art methodologies designed to advance your understanding of complex cellular behaviors within 3D environments.
Figure 1. Time-course of U-87 MG glioblastoma spheroid invasion into BMM. U-87 MG spheroid 3D invasion into BMM was monitored and quantified up to 72 hr using an imaging cytometer. (A) Representative images and (B) quantification of tumor cell invasion is shown. Bar = 500 μm.
1. Vinci M, Box C, Eccles SA. Three-dimensional (3D) tumor spheroid invasion assay. J Vis Exp. 2015;(99):e52686. Published 2015 May 1. doi:10.3791/52686