Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons in the brain and spinal cord. Motor neuron-dependent myocontraction refers to the process by which motor neurons transmit signals to muscle fibers, leading to muscle contraction.

Neuromuscular Co-culture ALS Models show potential in evaluating neurotrophic activity and screening therapeutics for various neuromuscular diseases. Creative Bioarray's expertise enables the observation of motor neuron-dependent myocontraction, facilitating the evaluation of compound efficacy in enhancing spinal motor neuron functionality.

Evaluation of Motor Neuron-dependent Myocontraction

  • Contractile activity
  • Innervation rate 
  • Innervation area
* For scientific research only

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