Ferroptosis is a method of cell death that has only been discovered in recent years. The ferroptosis process involves multiple mechanisms and is precisely regulated by signal pathways. Not sure why this sentence is in the intro paragraph focused on ferroptosis. Maybe add a transition stating how they are related? Therefore, further research on the mechanism of ferroptosis and its role in different types of diseases is of great significance for finding therapeutic targets for related diseases and the development of targeted drugs. Creative Bioarray provides intracellular iron level detection services to make your research on ferroptosis more accurate and convenient.


The essence of ferroptosis is the abnormal metabolism of lipid oxides in cells under the catalysis of iron ions. This process produces a large amount of lipid peroxide, which destroys the redox balance in the cell, attacks biological macromolecules, and triggers cell death.

Unlike classic apoptosis, there is no cell shrinkage or chromatin agglutination during ferroptosis, but mitochondria shrink and lipid peroxidation increases. Traditional inhibitors of apoptosis, autophagy, and pyrolysis cannot inhibit the ferroptosis process. But iron ion chelating agents can inhibit this process, indicating that ferroptosis is an iron ion-dependent process.

Our Services

Ferroptosis is an atypical way of cell death. It is very different from autophagy, apoptosis, and necrosis in cell morphology, induction and inhibition. Our services include but are not limited to:

Intracellular Iron Level Detection Service

Iron is an important trace element in the body. The abnormal distribution and content of iron in the body can affect normal physiological processes.

Phen Green SK (PGSK) is a cell membrane-permeable dye used to monitor the intracellular iron level in living cells via flow cytometry or confocal microscopy. It shows a diminished green autofluorescence of PGSK upon binding to sufficient cellular iron. Creative Bioarray provides a simple convenient means of measuring ferrous and/or ferric ions in samples.

Experimental Principle

In ferroptosis cells, the green fluorescence of PGSK will decreaseFigure1. In ferroptosis cells, the green fluorescence of PGSK will decrease (Hirayama T, et al. 2017).

Experiment Process

Experiment process

Customer Notice

Customers provide

  • Experimental samples
  • The purpose of the research
  • The requirements of the research

We deliver

  • High-quality test reagents
  • Standardized experimental process
  • Photos and relevant analysis data
  • Complete experiment report

Experiment cycle

The time depends on the experiment content

Advantages of Our Services

  • Advanced laboratory equipment

    We have many types of microscopes and other instruments with high resolution to provide you with clear and high-quality pictures.

  • Reliable

    The experimenters have many years of successful experiment experience and can guarantee the standard of experiment operation and experiment process.

  • Short time and low cost

    We provide customers with the most comprehensive services at the most favorable price and help customers improve the efficiency of research.

  • Safety

    All experiments have signed confidentiality agreements, focusing on protecting customer privacy.

If you are interested in our services, please contact us for more detailed information.


  1. Hirayama T, et al. (2017). Chemical tools for detecting Fe ions. Journal of clinical biochemistry and nutrition. 60(1):39-48.
* For scientific research only

Online Inquiry