Impaired Neurite Outgrowth in Alzheimer's Disease (AD):

  • AD pathology, particularly the presence of beta-amyloid plaques and tau tangles, can lead to impaired neurite outgrowth.
  • Neurons in affected areas may exhibit reduced capacity to extend their axons and dendrites, contributing to synaptic dysfunction and cognitive deficits.

Using immunostaining with a specific antibody, Creative Bioarray accurately labels and visualizes neuronal microtubules, enabling a quantitative evaluation of neurite outgrowth in response to different treatments. Understanding and potentially enhancing neurite outgrowth in Alzheimer's Disease represents a promising avenue for the development of treatments that aim to mitigate neurodegeneration and restore cognitive function.

Neurite Outgrowth Assay

Assessment of Neurite Outgrowth

  • Number of Cell Bodies
  • Number of Neurite Nodes
  • Length of Neurite
  • Number of Branch Points
* For scientific research only

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