Apoptosis or non-apoptotic death such as necrosis, autophagy and senescence is an important model for understanding intracellular functions. In recent years, more and more reports have pointed out that there is a correlation between cell senescence and cancer, as well as the mechanism of senescence and stem cell activity. Creative Bioarray can provide accurate and convenient cell senescence testing to help your research.


Cell Senescence Testing

Cell senescence is a complex physiological and pathological process involving multiple genes under the regulation of cell cycle, which has certain controllability. Cell senescence is considered a cancer inhibition mechanism and one of the potential causes of biological senescence.

Most normal cells are considered to have a limited ability to divide, and enter a state of senescence after being unable to divide. At this time, the cell is still alive, but the expression profile of the cell's gene and protein has largely changed.

The most notable feature of cell senescence is that cells still maintain metabolic activity for a long period of time. But because they are blocked in the G1 phase, they lose their ability to respond to mitogens and the ability to synthesize DNA and cannot enter the S phase.

Our Services

Cell senescence is a state of irreversible cell growth inhibition, which refers to the cell proliferation cessation after multiple generations or growth arrest due to stress response. Our services include but are not limited to:

SA-β-gal Detection Service

Senescent cells have remarkable characteristics. Senescence-associated β-galactosidase (SA-β-gal) is overexpressed in senescent cells, so it is regarded as one of the markers of cell senescence. β-galactosidase activity is easily detected in senescent cells, but not in presenescent cells, quiescent cells, immortal cells, or tumor cells.

SPiDER-βGal is a new type of green fluorescent dye to detect SA-β-gal. It has high cell membrane penetrability and will bind to protein after reacting with SA-β-gal and stay in the cell.

Based on a professional platform and rich experience, Creative Bioarray can provide rapid quantitative SA-β-gal detection service.

Experiment Process

Experiment process


  • Compared with traditional β-gal, SPiDER-βGal staining only takes 30 minutes.
  • Can be used for living cells or fixed cells.
  • Simple operation and high sensitivity.
  • You can use flow cytometry for quantitative analysis or live-cell observation under a fluorescent microscope.

Customer Notice

Customers provide

  • Cell suspension (number of cells≥106)
  • Research purpose
  • Test requirements

We deliver

  • High-quality test reagents
  • Experiment process and records
  • Photos and relevant analysis data
  • Complete experiment report

Experiment cycle

The time depends on the experiment content

Advantages of Our Services

  • High-quality products

    We provide detection reagents with high sensitivity and specificity.

  • Professional technicians

    We have rich operating experience and superb technology.

  • Short time and low cost

    We provide customers with the most comprehensive services at the most favorable price and help customers improve the efficiency of research.

  • Safety

    All experiments have signed confidentiality agreements, focusing on protecting customer privacy.

If you are interested in our services, please contact us for more detailed information.

* For scientific research only

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