Human umbilical vein endothelial cells (HUVECs) tube formation assay is one of the simple, but well-established in vitro angiogenesis assays based on the ability of ECs to form three-dimensional capillary-like tubular structure, which represents the later stage of the angiogenic process. During the assay, HUVEC cells differentiate, directionally migrate to align, branch, and form the polygonal networks of blood vessels.
Figure 1. The effects of test compound A on VEGF-induced HUVECs tube formation.
Creative Bioarray provides the HUVECs tube formation assay to support companies and academic laboratories in the development of angiogenic or inhibitory compounds.