Ferroptosis is a novel form of regulated cell death driven by iron-dependent lipid peroxidation that has been identified in recent years. Iron death-inducing factors can affect glutathione peroxidase directly or indirectly through different pathways, leading to decreased intracellular antioxidant capacity and accumulation of lipid reactive oxygen species (ROS), ultimately leading to oxidative cell death. A growing body of evidence suggests that. Dysfunctional iron death responses are associated with a variety of pathological conditions and diseases, such as neurodegenerative diseases, tissue ischemia-reperfusion injury, tumorigenesis, infections, and immune disorders. The iron death response can be fine-tuned through various oxidative stress and antioxidant defense pathways, in combination with metabolic, gene transcription, and protein degradation mechanisms.

Therefore, Creative Bioarray has developed a series of cell death and cell ferroptosis assays for researchers to analyze key steps in the iron death pathway. Our gold standard assay format, large panel of cell lines, and excellent service make us the contract research organization of choice for quality iron death assays. If you are interested in our products, please contact us for more details.

Advantages of Our Kits

  • All components required to run the assay are included.
  • Measure potency in single or co-culture models to interrogate the appropriate mechanism of action.
  • High batch-to-batch and intra-batch reproducibility.
  • Simple protocols with results in 24 hours or less.
  • Seamless method transfer for faster implementation of CMO, CDMO, or CRO.
  • Suitable for high throughput.
Product NumberProduct Name Price
FEK011 Lipid Peroxide (LPO) Assay Kit Inquiry
FEK012 Total Bile Acid (TBA) Assay Kit Inquiry
FEK013 Cysteine Assay Kit Inquiry
FEK014 Alanine Aminotransferase (ALT or SGPT) Activity Colorimetric Assay Kit Inquiry
FEK015 L-Alanine Assay Kit (Colorimetric/Flurometric) Inquiry
FEK016 Aspartate Aminotransferase (AST) Activity Assay Kit Inquiry
FEK017 Alanine Aminotransferase (ALT) Activity Assay Kit Inquiry
FEK018 Glutamate Assay Kit Inquiry
FEK019 Glutamate Dehydrogenase Activity Assay Kit Inquiry
FEK020 Glutamine Assay Kit Inquiry
* For scientific research only

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