Ferroptosis is a novel form of regulated cell death driven by iron-dependent lipid peroxidation that has been identified in recent years. Iron death-inducing factors can affect glutathione peroxidase directly or indirectly through different pathways, leading to decreased intracellular antioxidant capacity and accumulation of lipid reactive oxygen species (ROS), ultimately leading to oxidative cell death. A growing body of evidence suggests that. Dysfunctional iron death responses are associated with a variety of pathological conditions and diseases, such as neurodegenerative diseases, tissue ischemia-reperfusion injury, tumorigenesis, infections, and immune disorders. The iron death response can be fine-tuned through various oxidative stress and antioxidant defense pathways, in combination with metabolic, gene transcription, and protein degradation mechanisms.
Therefore, Creative Bioarray has developed a series of cell death and cell ferroptosis assays for researchers to analyze key steps in the iron death pathway. Our gold standard assay format, large panel of cell lines, and excellent service make us the contract research organization of choice for quality iron death assays. If you are interested in our products, please contact us for more details.
| Product Number | Product Name | Price |
|---|---|---|
| FEK021 | GSH/GSSG Assay Kit | Inquiry |
| FEK022 | GST Activity Assay Kit | Inquiry |
| FEK023 | Reduced Glutathione (GSH) Assay Kit | Inquiry |
| FEK024 | Glucose-6-phosphate Colorimetric Assay Kit | Inquiry |
| FEK025 | Malate Dehydrogenase Assay | Inquiry |
| FEK026 | Blood Ammonia Assay Kit | Inquiry |
| FEK027 | Isocitrate Assay Kit | Inquiry |
| FEK028 | Phospholipid Assay Kit | Inquiry |
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