Caspase-1 Antibody
Product Category:
Apoptosis Inducers & Inhibitors
Description
A novel p53-activating tryptamine derivative that acts as a HDM2 (Human Double Minute-2) antagonist with potential antineoplastic activity. JNJ-26854165 inhibits the binding of the HDM2–p53 complex to the proteasome, blocking the degradation of p53. It displays potent anti-proliferative and apoptosis-inducing activity in a broad range of p53 wild type and mutant tumor models.
Product Information
Product Name
JNJ-26854165
Similar Name
1-N-[2-(1H-indol-3-yl)ethyl]-4-N-pyridin-4-ylbenzene-1,4-diamine; Serdemetan
Appearance
Off-white solid
Solubility
DMSO (>50 mg/ml)
Shipping Conditions
Gel Pack
Molecular Formula
C21H20N4
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