Caspase-1 Antibody
Product Category:
Apoptosis Inducers & Inhibitors
Description
GDC-0152 is a potent small molecule antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.
Product Information
Similar Name
(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-(4-phenylthiadiazol-5-yl)pyrrolidine-2-carboxamide, GDC0152, GDC 0152
Solubility
DMSO: 99 mg/ml (198.54 mM)
Shipping Conditions
Gel Pack
Molecular Formula
C25H34N6O3S
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