Caspase-1 Antibody

Product Category:
Apoptosis Inducers & Inhibitors

Description

Gambogic acid is a plant-derived natural product that acts as a caspase activator and apoptosis inducer, which causes an irreversible arrest in the G2/M phase of the cell cycle. It causes a decrease of Bcl-2 gene and an increase in Bax gene expression, which may result in apoptosis. Gambogic also acts as an inhibitor of A1 and Bcl-2 family proteins, including Bcl-xl, Bcl-2, Bcl-w, Bcl-B, Bfl-1, and Mcl-1.

Product Information

Product Number
CDAP-029
Product Name
Gambogic acid
cas
2752-65-0
Similar Name
(Z)-4-((1S,3aR,5S,11R,14aS)-8-hydroxy-2,2,11-trimethyl-13-(3-methylbut-2-en-1-yl)-11-(4-methylpent-3-en-1-yl)-4,7-dioxo-2,3a,4,5,7,11-hexahydro-1H-1,5-methanofuro[3,2-g]pyrano[3,2-b]xanthen-3a-yl)-2-methylbut-2-enoic acid
Storage Conditions
-20°C
Molecular Weight
628.75
Appearance
Orange solid
Solubility
DMSO (>25 mg/ml) or EtOH (~20 mg/ml)
Shipping Conditions
Gel Pack
Purity
≥95%
Molecular Formula
C38H44O8

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