Caspase-1 Antibody
Product Category:
DNA Fragmentation
Description
Deoxyribonuclease I (usually called DNase I), is an endonuclease coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. It acts on single-stranded DNA, double-stranded DNA, and chromatin. In addition to its role as a waste-management endonuclease, it has been suggested to be one of the deoxyribonucleases responsible for DNA fragmentation during apoptosis. This kit allows for quantitative evaluation of DNAse I activity of purified enzymes and their inhibitors as well as comparative examination of DNAse I activity in biological samples.
Product Information
Product Name
DNAse I Activity Assay Kit (Fluorometric)
Application
• Measurement of DNAse I activity of purified proteins• Quantitative analysis of DNAse I mutants and inhibitors • Comparative examination of DNAse I activity in biological samples
Detection Method
Fluorescence (Ex/Em 651/681 nm)
Shipping Conditions
Gel Pack
Species Reactivity
Eukaryotes
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