CAY10603

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Caspase-1 Antibody

Product Category:
Apoptosis Inducers & Inhibitors

Description

CAY10603 is a selective inhibitor of Histone deacetylase 6 (HDAC6). The IC₅₀ for inhibition of HDAC6 is 2 pM, in vitro. CAY10603 inhibited growth of various pancreatic cell lines with IC₅₀ values ranging from 0.1 μM to 1 μM. It induced apoptosis and inhibited the proliferation of lung adenocarcinoma cells.

Product Information

Product Number
CDAP-043
Product Name
CAY10603
cas
1045792-66-2
Similar Name
HDAC6 Inhibitor, tert-butyl N-[4-[3-[[7-(hydroxyamino)-7-oxoheptyl]carbamoyl]-1,2-oxazol-5-yl]phenyl]carbamate, tert-butyl N-[4-[3-[[7-(hydroxyamino)-7-oxoheptyl]carbamoyl]-1,2-oxazol-5-yl]phenyl]carbamate, {4-[3-(6-Hydroxycarbamoylhexylcarbamoyl)isoxazol-5-yl]phenyl}carbamic acid tert-butyl ester, Histone Deacetylase Inhibitor VIII
Storage Conditions
-20ºC
Molecular Weight
446.50
Appearance
Crystalline solid
Solubility
~15 mg/ml in DMSO
MDL Number
MFCD17010286
Shipping Conditions
RT
Purity
>98%
Molecular Formula
C22H30N4O6

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