Caspase-1 Antibody

Product Category:
Apoptosis Inducers & Inhibitors

Description

Birinapant is a SMAC (synthetic small molecule and peptidomimetic of second mitochondrial-derived activator of caspases) mimetic and IAP (Inhibitor of Apoptosis Protein) antagonist with potential antineoplastic activity. Birinapant binds to and inhibits the activity of IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2. Since IAPs shield cancer cells from the apoptosis process, this agent may restore and promote the induction of apoptosis through apoptotic signaling pathways in cancer cells.

Product Information

Product Number
CDAP-050
Product Name
Birinapant
cas
1260251-31-7
Similar Name
(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methyl]-1H-indol-2-yl]-1H-indol-3-yl]methyl]-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl]-2-(methylamino)propanamide; TL32711; SMAC mimetic
Storage Conditions
-20 ̊C
Molecular Weight
806.94
Appearance
White to off-white solid
Solubility
DMSO (>50 mg/ml)
Shipping Conditions
Gel Pack
Purity
>98% by HPLC
Molecular Formula
C42H56F2N8O6

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