Caspase-1 Antibody
Product Category:
Apoptosis Inducers & Inhibitors
Description
A potent and selective BAX activator (EC₅₀ = 3.3 μM). BAM7 directly binds at the BH3-binding site; selective for BAX over other antiapoptotic and proapoptotic proteins. BAM7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death. BAM7 selectively induces BAX-mediated apoptosis by triggering the hallmark features of intracellular BAX activation. BAM7 only kills the cell line that contains BAX, eliciting the biochemical and morphologic features of BAX-mediated apoptosis.
Product Information
Product Name
BAX Activator, BAM7
Similar Name
3-Methyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
Solubility
DMSO (~ 2 mg/ml)
Shipping Conditions
Gel Pack
Molecular Formula
C21H19N5O2S
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