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Autophagy is a biological process that exists in all eukaryotic systems to help cells maintain homeostasis. Autophagy is a non-apoptotic form of programmed cell death, which has different signaling pathways and regulatory factors from apoptosis. The degradation and recycling of cellular components in autophagy are controlled, and there are three different forms, including macroautophagy, microautophagy and chaperone-mediated autophagy. Autophagy is regulated by the activity of mTOR1 kinase, which is inhibited when the autophagy process is induced. Next, the LC3 protein assists in the formation of autophagosomes, and the mature autophagosomes bind to lysosomes and are degraded by hydrolytic enzymes in the lysosomes.

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CDAP-057 24(S)-Hydroxycholesterol Inquiry
CDAP-058 Anisomycin Inquiry
CDAP-059 MX1013 Inquiry
CDAP-060 Emricasan Inquiry
CDAP-061 MG 132 Inquiry
CDAP-062 NQDI 1 Inquiry
CDAP-063 MSC 2032964A Inquiry
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CDAP-065 PD 150606 Inquiry
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