Caspase-1 Antibody
Product Category:
Autophagy Antibodies
Description
Autophagy, the process of bulk degradation of cellular proteins throμgh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) throμgh phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is APG7 which was identified in yeast as a ubiquitin-E1-like enzyme; this function is conserved in the mammalian homolog (4). In mammalian cells, APG7 is essential for autophagy conjμgation systems, autophagosome formation, starvation-induced bulk degradation of proteins and organelles. It has been sμggested that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death.
Product Information
Product Name
APG7/ATG7 Antibody
Similar Name
APG7L , ATG7 , DKFZp434N0735 , GSA7
Storage Conditions
-20 °C
USAGE
For Research Use Only! Not For Use in Humans.
Appearance
Colorless liquid
Shipping Conditions
Gel Pack
Species Reactivity
Human, mouse
Click here to find related products
If you have any questions or needs, please contact us for more detailed information.
