Caspase-1 Antibody
Product Category:
Autophagy Antibodies
Description
Autophagy, the process of bulk degradation of cellular proteins throμgh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) throμgh phosphorylation of autophagy protein APG1. Another member of the autophagy protein family is APG10 (Also called ATG10, APG10L), an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjμgation and the modification of a soluble form of MAP-LC3, a homolog of yeast Apg8, to a membrane-bound form. ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7. Multiple isoforms of ATG10 are known to exist.
Product Information
Product Name
APG10/ATG10 Antibody
Similar Name
APG10 , APG10L, ATG10 , DKFZP586I0418 , FLJ13954 , pp12616
USAGE
For Research Use Only! Not For Use in Humans.
Appearance
Colorless liquid
Shipping Conditions
Gel Pack
Species Reactivity
Human, mouse, rat
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