Caspase-1 Antibody
Product Category:
Autophagy Antibodies
Description
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart sμggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Product Information
Product Name
AMPK⍺2 Antibody
Application
ELISA, Western blot, Immunohistochemistry
Storage Conditions
-20 °C
USAGE
For Research Use Only! Not For Use in Humans.
Appearance
Colorless liquid
Shipping Conditions
Gel Pack
Species Reactivity
Human, mouse
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